Amin A Nomeir: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

High-performance liquid chromatographic analysis and stability of anti-tumor agent temozolomide in human plasma

Hong Kim, Paul Likhari, Donald Parker, Paul Statkevich, Aliceann Marco, Chin-Chung Lin, Amin A. Nomeir

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2001

Language:

english

File:

PDF, 94 KB

english, 2001

2

Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice

Ming Liu, Matthew S. Bryant, Jianping Chen, Suining Lee, Bohdan Yaremko, Zujun Li, Janet Dell, Phil Lipari, Michael Malkowski, Nicholas Prioli, Randall R. Rossman, Walter A. Korfmacher, Amin A. Nomeir

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 323 KB

english, 1999

3

Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048)

Amin A. Nomeir, Birendra N. Pramanik, Larry Heimark, Frank Bennett, John Veals, Peter Bartner, Maryjane Hilbert, Anil Saksena, Paul McNamara, Viyyoor Girijavallabhan, Ashit K. Ganguly, Raymond Lovey,

Journal:

Journal of Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 722 KB

english, 2008

4

Structure−Activity Relationship of 3-Substituted N -(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11 H -benzo[5,6]cyclohepta[1,2- b ]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase: Design and Synthesis of in Vivo Active Antitumor Compounds

Njoroge, F. George, Vibulbhan, Bancha, Rane, Dinananth F., Bishop, W. Robert, Petrin, Joanne, Patton, Robert, Bryant, Mathew S., Chen, K.-J., Nomeir, Amin A., Lin, C.-C., Liu, Ming, King, Ivan, Chen,

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 411 KB

english, 1997

5

Bridgehead Modification of Trihalocycloheptabenzopyridine Lead to a Potent Farnesyl Protein Transferase Inhibitor with Improved Oral Metabolic Stability.

F. George Njoroge, Bancha Vibulbhan, Xiongwei Shi, Corey Strickland, Paul Kirschmeier, Robert Bishop, Amin Nomeir, Viyyoor Girijavallabhan

Journal:

Year:

2005

File:

PDF, 13 KB

2005

6

Small conformationally restricted piperidine N-arylsulfonamides as orally active γ-secretase inhibitors

Hubert Josien, Thomas Bara, Murali Rajagopalan, Theodros Asberom, John W. Clader, Leonard Favreau, William J. Greenlee, Lynn A. Hyde, Amin A. Nomeir, Eric M. Parker, Dmitri A. Pissarnitski, Lixin Song

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 209 KB

english, 2007

7

In vitro metabolism of EPN and EPNO in susceptible and resistant strains of house flies

Amin A. Nomeir, Nicolas P. Hajjar, Ernest Hodgson, Walter C. Dauterman

Journal:

Pesticide Biochemistry and Physiology

Year:

1980

Language:

english

File:

PDF, 626 KB

english, 1980

8

High-Throughput Evaluation of CYP1A1 and 2B1 Induction in Rat Liver Slices Using a Semi-Automated System

Palamanda, Jairam, Lin, Xinjie, Kumari, Pramila, Nomeir, Amin

Journal:

Drug Metabolism Letters

Year:

2009

Language:

english

File:

PDF, 246 KB

english, 2009

9

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

Hong Kim, Wenqing Feng, Tze-Ming Chan, Diane Rindgen, Matthew Bryant, Kathleen A. Cox, Yan Xia, Gregory Reichard, Sunil Paliwal, David Hesk, Jairam Palamanda, Ronald E. White, Amin A. Nomeir

Journal:

Journal of Separation Science

Year:

2002

Language:

english

File:

PDF, 221 KB

english, 2002

10

Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice

Eva-Pia Reich, Long Cui, Lily Yang, Catherine Pugliese-Sivo, Andrei Golovko, Mary Petro, Galya Vassileva, Inhou Chu, Amin A. Nomeir, Li-Kang Zhang, Xian Liang, Joseph A. Kozlowski, Satwant K. Narula,

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 328 KB

english, 2005

11

Estimation of the extent of oral absorption in animals from oral and intravenous pharmacokinetic data in drug discovery

Amin A. Nomeir, Richard Morrison, Daniel Prelusky, Walter Korfmacher, Lisa Broske, David Hesk, Paul McNamara, Hong Mei

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

12

Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2

Gopal Krishna, Kwang-jong Chen, Chin-chung Lin, Amin A Nomeir

Journal:

International Journal of Pharmaceutics

Year:

2001

Language:

english

File:

PDF, 215 KB

english, 2001

13

Identification of a novel 1′-[5-((3,5-Dichlorobenzoyl)methylamino)-3-(3,4-dichlorophenyl)-4-(methoxyimino)pentyl]-2-oxo-(1,4′-bipiperidine) as a Dual NK1/NK2 antagonist

Pauline C Ting, Joe F Lee, Neng-Yang Shih, John J Piwinski, John C Anthes, Richard W Chapman, Charles A Rizzo, John A Hey, Kwokei Ng, Amin A Nomeir

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

14

Design, synthesis, and structure–activity relationship studies of N-arylsulfonyl morpholines as γ-secretase inhibitors

Hongmei Li, Ruo Xu, David Cole, John W. Clader, William J. Greenlee, Amin A. Nomeir, Lixin Song, Lili Zhang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

15

Enhanced FTase activity achieved via piperazine interaction with catalytic zinc

F. George Njoroge, Bancha Vibulbhan, Patrick Pinto, Corey Strickland, W. Robert Bishop, Amin Nomeir, Vivyoor Girijavallabhan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 208 KB

english, 2006

16

METABOLISM AND DISPOSITION OF DIMETHYL HYDROGEN PHOSPHITE IN RATS AND MICE

Nomeir, Amin A., Matthews, H. B.

Journal:

Journal of Toxicology and Environmental Health

Year:

1997

Language:

english

File:

PDF, 461 KB

english, 1997

17

Pharmacokinetics of the active antifungal enantiomer, SCH 42427 (RR), and evaluation of its chiral inversion in animals following its oral administration and the oral administration of its racemate genaconazole (RR/SS)

Hong Kim, Elaine Radwanski, Raymond Lovey, Chin-Chung Lin, Amin A. Nomeir

Journal:

Year:

2002

Language:

english

File:

PDF, 95 KB

english, 2002

18

High-performance liquid chromatographic analysis on radial compression column of the neurotoxic tri-o-cresyl phosphate and metabolites

Amin A. Nomeir, Mohamed B. Abou-Donia

Journal:

Analytical Biochemistry

Year:

1983

Language:

english

File:

PDF, 597 KB

english, 1983

19

Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype Activity

Coburn, Craig A., Meinke, Peter T., Chang, Wei, Fandozzi, Christine M., Graham, Donald J., Hu, Bin, Huang, Qian, Kargman, Stacia, Kozlowski, Joseph, Liu, Rong, McCauley, John A., Nomeir, Amin A., Soll

Journal:

Year:

2013

Language:

english

File:

PDF, 463 KB

english, 2013

20

High-performance liquid chromatographic analysis of the anti-tumor agent SCH 66336 in cynomolgus monkey plasma and evaluation of its chiral inversion in animals

Hong Kim, Paul Likhari, Chin-Chung Lin, Amin A Nomeir

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 168 KB

english, 1999

21

Influence of Food on the Oral Bioavailability of Loratadine and Pseudoephedrine from Extended-Release Tablets in Healthy Volunteers

Nomeir, Amin A., Mojaverian, Parviz, Kosoglou, Teddy, Affrime, Melton B., Nezamis, Jim, Radwanski, Elaine, Lin, Chin-Chung, Cayen, Mitchell N.

Journal:

Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.32 MB

english, 1996

22

Discovery of a novel, potent and orally active series of γ-lactams as selective NK1 antagonists

Sunil Paliwal, Gregory A. Reichard, Sapna Shah, Michelle Laci Wrobleski, Cheng Wang, Carmine Stengone, Hon-Chung Tsui, Dong Xiao, Ruth A. Duffy, Jean E. Lachowicz, Amin A. Nomeir, Geoffrey B. Varty, N

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

23

Bridgehead modification of trihalocycloheptabenzopyridine lead to a potent farnesyl protein transferase inhibitor with improved oral metabolic stability

F. George Njoroge, Bancha Vibulbhan, Xiongwei Shi, Corey Strickland, Paul Kirschmeier, Robert Bishop, Amin Nomeir, Viyyoor Girijavallabhan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

24

Comparative toxicity, cholinergic effects, and tissue levels of S,S,S,-tri-n-butyl phosphorotrithioate (DEF) to channel catfish (ictalurus punctatus) and blue crabs (callinectes sapidus)

Clifford Habig, Richard T. Digiulio, Amin A. Nomeir, Mohamed B. Abou-Donia

Journal:

Aquatic Toxicology

Year:

1986

Language:

english

File:

PDF, 646 KB

english, 1986

25

Determination of 1-methoxy-2-propanol and its metabolite 1,2-propanediol in rat and mouse plasma by gas chromatography

Nicholas F. Ferrala, Burhan I. Ghanayem, Amin A. Nomeir

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1994

Language:

english

File:

PDF, 499 KB

english, 1994

26

High-performance liquid chromatographic determination and stability of 5-(3-methyltriazen-1-yl)-imidazo-4-carboximide, the biologically active product of the antitumor agent temozolomide, in human plasma

Hong Ki Kim, Chin-chung Lin, Donald Parker, John Veals, Josephine Lim, Paul Likhari, Paul Statkevich, Aliceann Marco, Amin A Nomeir

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 129 KB

english, 1997

27

Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes

Inhou Chu, Leonard Favreau, Tony Soares, Chin-chung Lin, Amin A. Nomeir

Journal:

Rapid Communications in Mass Spectrometry

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

28

Structure-activity studies on the mutagenicity of tris(2,3-dibromopropyl) phosphate (tris-BP) and its metabolites in salmonella

Errol Zeiger, Dennis A. Pagano, Amin A. Nomeir

Journal:

Environmental and Molecular Mutagenesis

Year:

1982

Language:

english

File:

PDF, 322 KB

english, 1982

29

High-performance liquid chromatographic analysis of the anti-fungal agent SCH 56592 in dog serum

Hong Kim, Paul Likhari, Pramila Kumari, Chin-Chung Lin, Amin A Nomeir

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

30

Potent, Selective, and Orally Bioavailable Tricyclic Pyridyl Acetamide N -Oxide Inhibitors of Farnesyl Protein Transferase with Enhanced in Vivo Antitumor Activity

Njoroge, F. George, Vibulbhan, Bancha, Pinto, Patrick, Bishop, W. Robert, Bryant, Mathew S., Nomeir, Amin A., Lin, C.-C., Liu, Ming, Doll, Ronald J., Girijavallabhan, V., Ganguly, Ashit K.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 132 KB

english, 1998

31

Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active γ-secretase inhibitors

Mark D. McBriar, John W. Clader, Inhou Chu, Robert A. Del Vecchio, Leonard Favreau, William J. Greenlee, Lynn A. Hyde, Amin A. Nomeir, Eric M. Parker, Dmitri A. Pissarnitski, Lixin Song, Lili Zhang, Z

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 252 KB

english, 2008

32

Liquid chromatographic analysis, stability and protein binding studies of the anti-HIV agent benzoic acid, 2-chloro-5[[(1-methylethoxy)thioxomethyl]amino]-,1-methylethyl ester

Amin A. Nomeir, Madeline F. McComish, Amy L. Mongan, Joseph M. Covey, Nicholas F. Ferrala

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1994

Language:

english

File:

PDF, 587 KB

english, 1994

33

A computer program for automated data evaluation to support in vitro higher-throughput screening for drug metabolism and pharmacokinetics attributes

Eliza N. Fung, Inhou Chu, Amin A. Nomeir

Journal:

Rapid Communications in Mass Spectrometry

Year:

2004

Language:

english

File:

PDF, 1.18 MB

english, 2004

34

Atropisomeric trihalobenzocycloheptapyridine analogues provide stereoselective FPT inhibitors with antitumor activity

F.George Njoroge, Bancha Vibulbhan, W.Robert Bishop, Paul Kirschmeier, Mathew S. Bryant, Amin A. Nomeir, Ming Liu, Ronald J. Doll, Viyyoor M. Girijavallabhan, Ashit K. Ganguly

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 258 KB

english, 1999

35

Pulmonary absorption and disposition of [ 14 C]thiophene in rats following nose‐only inhalation exposure

Nomeir, Amin A., Markham, Peter M., Chadwick, Marjory

Journal:

Journal of Toxicology and Environmental Health

Year:

1993

Language:

english

File:

PDF, 937 KB

english, 1993

36

Novel in vivo procedure for rapid pharmacokinetic screening of discovery compounds in rats

Kathleen A. Cox, Kimberly Dunn-Meynell, Walter A. Korfmacher, Lisa Broske, Amin A. Nomeir, Chin-Chung Lin, Mitchell N. Cayen, William H. Barr

Journal:

Drug Discovery Today

Year:

1999

Language:

english

File:

PDF, 200 KB

english, 1999

37

In vitro degradation of malathion by mouse liver

Amin A. Nomeir, Walter C. Dauterman

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 247 KB

english, 1978

38

New class of azaheptapyridine FPT inhibitors as potential cancer therapy agents

Zhu, Hugh Y., Desai, Jagdish, Cooper, Alan B., Wang, James, Rane, Dinananth F., Kirschmeier, Paul, Strickland, Corey, Liu, Ming, Nomeir, Amin A., Girijavallabhan, Viyyoor M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

39

ChemInform Abstract: Identification of a Novel 1′-[5-((3,5-Dichlorobenzoyl)methylamino)-3-(3,4-dichlorophenyl)-4- (methoxyimino)pentyl]-2-oxo-(1,4′-bipiperidine) (I) as a Dual NK1/NK2 Antagonist.

Pauline C. Ting, Joe F. Lee, Neng-Yang Shih, John J. Piwinski, John C. Anthes, Richard W. Chapman, Charles A. Rizzo, John A. Hey, Kwokei Ng, Amin A. Nomeir

Journal:

Year:

2002

File:

PDF, 31 KB

2002

40

Use of high-performance liquid chromatographic and microbiological analyses for evaluating the presence or absence of active metabolites of the antifungal posaconazole in human plasma

Hong Kim, Pramila Kumari, Mark Laughlin, Mary Jane Hilbert, Stephen R Indelicato, Josephine Lim, Chin-Chung Lin, Amin A Nomeir

Journal:

Journal of Chromatography A

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

41

Validation of a rapid microtiter plate assay to conduct cytochrome P450 2D6 enzyme inhibition studies

Jairam R Palamanda, Leonard Favreau, Chin-chung Lin, Amin A Nomeir

Journal:

Drug Discovery Today

Year:

1998

Language:

english

File:

PDF, 153 KB

english, 1998

42

Utility of Mass Spectrometry for In-Vitro ADME Assays

Chu, Inhou, A.Nomeir, Amin

Journal:

Current Drug Metabolism

Year:

2006

Language:

english

File:

PDF, 365 KB

english, 2006

43

Studies on the metabolism of the neurotoxic tri-o-cresyl phosphate. Synthesis and identification by infrared, proton nuclear magnetic resonance and mass spectrometry of five of its metabolites

Amin A. Nomeir, Mohamed B. Abou-Donia

Journal:

Year:

1986

Language:

english

File:

PDF, 701 KB

english, 1986

44

High-performance liquid chromatographic analysis of the D4 receptor antagonist SCH 66712 in rat plasma

Hong Kim, David G Schuessler, Cynthia A Bach, Chin-Chung Lin, Amin A Nomeir

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

45

Simultaneous high-performance liquid chromatographic determination of SCH 59884 (phosphate ester prodrug of SCH 56592), SCH 207962 and SCH 56592 in dog plasma

Hong Kim, Pramila Kumari, Chin-Chung Lin, Amin A. Nomeir

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2002

Language:

english

File:

PDF, 159 KB

english, 2002

46

Comparative disposition of 2,3‐epoxy‐1‐propanol (glycidol) in rats following oral and intravenous administration

Nomeir, Amin A., Silveira, Denise M., Ferrala, Nicholas F., Markham, Peter M., McComish, Madeline F., Ghanayem, Burhan I., Chadwick, Marjory

Journal:

Journal of Toxicology and Environmental Health

Year:

1995

Language:

english

File:

PDF, 865 KB

english, 1995

47

Studies on the metabolism of the neurotoxic tri-o-cresyl phosphate. Distribution, excretion, and metabolism in male cats after a single, dermal application

Amin A. Nomeir, Mohamed B. Abou-Donia

Journal:

Year:

1986

Language:

english

File:

PDF, 1.06 MB

english, 1986

48

Effects of felbamate on the pharmacokinetics of a low-dose combination oral contraceptive

Saano, Veijo, Glue, Paul, Banfield, Christopher R., Reidenberg, Pascale, Colucci, Robert D., Meehan, Jeffrey W., Haring, Pertti, Radwanski, Elaine, Nomeir, Amin, Lin, Chin-Chung, Jensen, Peder K., Aff

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 930 KB

english, 1995

49

Pharmacokinetic Drug Interaction Study

Radwanski, Elaine, Nomeir, Amin, Lin, Chin-Chung, Cutler, David, Affrime, Melton

Journal:

American Journal of Therapeutics

Year:

1998

File:

PDF, 460 KB

1998

50

METABOLISM AND DISPOSITION OF DIMETHYL HYDROGEN PHOSPHITE IN RATS AND MICE

Nomeir, Amin A., Matthews, H. B.

Journal:

Journal of Toxicology and Environmental Health

Year:

1997

Language:

english

File:

PDF, 671 KB

english, 1997

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски